Jakub Tolar Selected Research

Epidermolysis Bullosa

12/2018	A 3D in vitro model of the dermoepidermal junction amenable to mechanical testing.
1/2018	Inside out: regenerative medicine for recessive dystrophic epidermolysis bullosa.
6/2016	Toxic Epidermal Necrolysis in Recessive Dystrophic Epidermolysis Bullosa following Bone Marrow Transplantation.
6/2015	Placenta-based therapies for the treatment of epidermolysis bullosa.
6/2015	From marrow to matrix: novel gene and cell therapies for epidermolysis bullosa.
1/2015	The three-body problem of therapy with induced pluripotent stem cells.
6/2013	TALEN-based gene correction for epidermolysis bullosa.
6/2011	Concise review: Transplantation of human hematopoietic cells for extracellular matrix protein deficiency in epidermolysis bullosa.
1/2009	Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells.

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Jakub Tolar Research Topics

Disease

22	Mucopolysaccharidosis I (Hurler Syndrome) 11/2020 - 01/2006
21	Epidermolysis Bullosa Dystrophica (Dystrophic Epidermolysis Bullosa) 01/2022 - 08/2010
18	Neoplasms (Cancer) 01/2021 - 06/2003
13	Graft vs Host Disease (Graft-Versus-Host Disease) 10/2021 - 11/2007
9	Epidermolysis Bullosa 12/2018 - 01/2009
7	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2020 - 01/2010
6	Inflammation (Inflammations) 01/2022 - 01/2014
6	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 01/2012 - 01/2010
5	Wounds and Injuries (Trauma) 01/2022 - 12/2012
5	Disease Progression 01/2015 - 05/2011
4	Dyskeratosis Congenita (X-Linked Dyskeratosis Congenita) 10/2018 - 08/2013
4	Fanconi Anemia (Fanconi's Anemia) 09/2017 - 07/2011
4	Blister (Bulla) 12/2012 - 08/2010
4	Aplastic Anemia (Anemia, Hypoplastic) 07/2012 - 09/2006
3	Inborn Genetic Diseases (Disease, Hereditary) 01/2020 - 01/2018
3	Central Nervous System Diseases (CNS Diseases) 10/2017 - 08/2008
2	Skin Diseases (Skin Disease) 01/2021 - 02/2014
2	Ventricular Fibrillation 12/2020 - 12/2020
2	Heart Arrest (Cardiac Arrest) 12/2020 - 12/2020
2	Out-of-Hospital Cardiac Arrest 12/2020 - 12/2020
2	Osteopetrosis 11/2019 - 09/2009
2	Bronchiolitis Obliterans Syndrome 12/2018 - 09/2011
2	Congenital Bone Marrow Failure Syndromes 09/2017 - 05/2017
2	Diamond-Blackfan Anemia (Anemia, Diamond Blackfan) 09/2017 - 05/2017
2	Metachromatic Leukodystrophy (Sulfatide Lipidosis) 04/2016 - 01/2010
2	Myocardial Infarction 01/2015 - 04/2007
2	Neurologic Manifestations (Neurological Manifestations) 01/2012 - 08/2011
2	Mucopolysaccharidoses 07/2011 - 02/2011
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 06/2008 - 07/2005
2	Leukemia 03/2008 - 04/2004
1	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 05/2022
1	Retinoblastoma (Glioblastoma, Retinal) 01/2021
1	Ventricular Tachycardia 12/2020
1	Junctional Epidermolysis Bullosa (Epidermolysis Bullosa Letalis) 01/2020
1	Gaucher Disease (Gaucher's Disease) 01/2020
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2020
1	Carcinogenesis 02/2019
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 02/2019
1	Lymphopenia (Lymphocytopenia) 12/2018
1	Premature Aging 12/2018
1	Hematologic Neoplasms (Hematological Malignancy) 01/2018
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2018

Drug/Important Bio-Agent (IBA)

17	Collagen Type VIIIBA 01/2022 - 01/2009
12	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2006
10	Iduronidase (alpha-L-Iduronidase)IBA 01/2017 - 01/2006
9	GlycosaminoglycansIBA 01/2022 - 01/2006
8	EnzymesIBA 11/2019 - 01/2006
4	Biomarkers (Surrogate Marker)IBA 11/2019 - 10/2011
4	CytokinesIBA 04/2016 - 03/2008
3	CollagenIBA 01/2022 - 08/2012
3	LipidsIBA 11/2020 - 09/2011
2	Isoantigens (Alloantigen)IBA 10/2021 - 10/2009
2	Chimeric Antigen ReceptorsIBA 01/2018 - 03/2008
2	fludarabineIBA 10/2017 - 07/2012
2	AntigensIBA 01/2016 - 03/2008
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 07/2012 - 09/2006
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2012 - 10/2011
2	DNA (Deoxyribonucleic Acid)IBA 03/2011 - 07/2007
1	Peptides (Polypeptides)IBA 05/2022
1	ElastinIBA 01/2022
1	Retinaldehyde (Retinal)IBA 01/2021
1	Differentiation AntigensIBA 01/2021
1	Nonsense Codon (Nonsense Mutation)IBA 01/2020
1	Ambroxol (Mucosolvan)IBA 01/2020
1	Pharmaceutical PreparationsIBA 01/2020
1	ChemokinesIBA 02/2019
1	Interleukin-8 (Interleukin 8)IBA 02/2019
1	Tannic Acid FDA Link 02/2019
1	SolutionsIBA 02/2019
1	Chondroitin Sulfates (Chondroitin Sulfate)IBA 02/2019
1	pullulanIBA 02/2019
1	ProteomeIBA 12/2018
1	Vitamin D FDA LinkGeneric 12/2018
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 12/2018
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2018
1	Immune Checkpoint InhibitorsIBA 01/2018
1	Small Cytoplasmic RNAIBA 01/2018
1	Immunoglobulins (Immunoglobulin)IBA 01/2018
1	Ataxin-1IBA 01/2018
1	RNA (Ribonucleic Acid)IBA 01/2018
1	polyglutamineIBA 01/2018
1	SpermineIBA 10/2017

Therapy/Procedure

32	Therapeutics 11/2021 - 07/2005
21	Cell Transplantation 01/2020 - 01/2008
18	Transplantation 09/2017 - 06/2003
8	Bone Marrow Transplantation (Transplantation, Bone Marrow) 06/2016 - 04/2004
6	Hematopoietic Stem Cell Transplantation 11/2019 - 03/2008
4	Stem Cell Transplantation 10/2018 - 08/2010
3	Homologous Transplantation 01/2022 - 01/2010
3	Aftercare (After-Treatment) 01/2022 - 04/2004
3	Immunotherapy 01/2018 - 10/2009
3	Drug Therapy (Chemotherapy) 09/2012 - 04/2006
2	Cardiopulmonary Resuscitation (CPR) 12/2020 - 12/2020
2	Resuscitation 12/2020 - 12/2020
2	Extracorporeal Membrane Oxygenation 12/2020 - 12/2020
2	Enzyme Replacement Therapy 03/2016 - 02/2013
1	Immunomodulation 01/2021
1	Advanced Cardiac Life Support (Life Support, Advanced Cardiac) 12/2020
1	Palliative Care (Palliative Therapy) 01/2020
1	Traction 01/2018